Development PDE5 inhibitor for antimalarials
On the basis of a common homology sequence in PDE's between human and malarial parasite, we aimed to develop antimalarial leads
Molecule libraries
Enrichment of heterocycle molecule libraries through easier protocols
Tandem/ Cascade reactions
Metal free/ catalysed activation of C=N based cyclizations to procure various medicinally important heterocyclic scaffolds.
2-Oxo driven chemistry
Study of distinctive 2-Oxo based electrophilic reaction with few nucleophiles